How to Fix the Gut Microbiome

Your gut microbiome is home to trillions of bacteria, fungi, and other microorganisms that play a powerful role in how you feel every day. These microbes influence digestion, immunity, mood, metabolism, and even inflammation throughout your body. When this delicate ecosystem becomes unbalanced, it can lead to symptoms far beyond your stomach. Fatigue, anxiety, skin problems, and chronic pain often trace back to what’s happening in your gut.

At Dr. Branham’s functional medicine practice in St. Louis, restoring gut health and the gut microbiome isn’t about quick fixes. It’s about uncovering why your microbiome became disrupted in the first place and creating a plan to help it thrive again naturally.

Why the Gut Microbiome Matters

Your gut does far more than break down food. It acts as an interface between the outside world and your internal systems, constantly communicating with your brain, immune system, and hormones. A balanced microbiome helps your body do the following:

  • Break down and absorb nutrients efficiently
  • Produce vitamins such as B12 and K2
  • Maintain a strong immune defense
  • Protect the gut lining from toxins and pathogens
  • Regulate inflammation and metabolism
  • Support neurotransmitters such as serotonin that influence mood

When the microbiome is healthy, you feel energetic, focused, and resilient. When your gut microbiome needs fixing, a condition known as dysbiosis, you might feel bloated, fatigued, anxious, or inflamed without realizing the root cause.

Six Common Causes of Microbiome Imbalance

The modern lifestyle has made issues with the gut microbiome extremely common. Dr. Branham often finds that several factors work together to disrupt microbial diversity and weaken the gut barrier.

  1. Poor Diet

A diet high in sugar, refined carbs, and processed foods, while also being low in fiber, starves beneficial bacteria. Healthy microbes thrive on plant fibers and polyphenols from fruits, vegetables, and herbs. When your diet lacks these nutrients, harmful bacteria and yeast can overgrow, leading to inflammation and digestive discomfort.

  1. Antibiotic Use

While antibiotics can be lifesaving, they don’t distinguish between good and bad bacteria. A single round can drastically alter gut flora, sometimes for months or even years. Without proper replenishment, beneficial species may never fully recover.

  1. Stress and Anxiety

Your gut and brain are in constant communication through the vagus nerve and chemical messengers. Chronic stress reduces digestive enzyme production, alters gut motility, and increases intestinal permeability. Over time, this stress response suppresses healthy bacteria and allows harmful strains to flourish.

  1. Leaky Gut (Intestinal Permeability)

When the intestinal lining becomes inflamed or damaged, tiny gaps allow food particles and toxins to enter the bloodstream. This triggers immune reactions, chronic inflammation, and even autoimmune responses. Leaky gut both results from and worsens microbiome imbalances.

  1. Environmental Toxins

Everyday exposure to pesticides, heavy metals, plastics, and other chemicals can harm gut bacteria and liver function. Your microbiome helps metabolize toxins, but when it’s compromised, detox pathways become sluggish and your body becomes more reactive.

  1. Sleep Disruption and Lack of Movement

Poor sleep quality and a sedentary lifestyle also contribute to microbiome dysfunction. Research shows that exercise helps beneficial bacteria thrive and improves microbial diversity, while disrupted circadian rhythms reduce healthy gut activity.

How Not to Fix the Gut Microbiome

When people experience digestive symptoms or fatigue, it’s easy to fall into habits that make gut health worse instead of better. Dr. Branham often reminds patients that restoring the microbiome requires changing the environment the bacteria live in, not masking the symptoms.

Here’s what doesn’t work in fixing the gut microbiome:

  1. Eating the Standard American Diet

Highly processed foods, refined sugars, seed oils, and artificial additives destroy microbial diversity. Yet many Americans eat this every day, and it’s known as the Standard American Diet. This type of diet promotes inflammation, increases bad bacteria, and leaves your gut lining weak and inflamed. If your daily routine includes fast food, soda, or low-fiber meals, your microbiome simply can’t thrive.

  1. Relying Solely on Medications

Acid blockers, antibiotics, and antacids can temporarily reduce discomfort, but they don’t fix the root cause of your gut microbiome’s dysbiosis. Long-term use can even make the problem worse by suppressing stomach acid, damaging gut lining, or wiping out beneficial bacteria. True healing requires restoring balance, not just managing symptoms.

  1. Thinking Gut Symptoms Are “Normal”

Bloating after meals, irregular bowel movements, or daily fatigue are not normal. Many people accept these symptoms as part of life, aging, or stress. But they’re actually signals that something deeper is off in the gut. Ignoring those messages allows imbalances to grow and inflammation to spread.

By changing these habits and taking a root-cause approach, you give your microbiome a chance to rebuild and your body a chance to truly heal.

The Functional Medicine Approach to Fixing the Gut

Dr. Branham’s approach to digestive health goes far beyond temporary symptom relief. Through advanced testing and personalized treatment, he identifies exactly what’s driving your imbalance, whether it’s an overgrowth of harmful bacteria, low microbial diversity, food sensitivities, or toxin exposure.

The functional medicine process of fixing the gut microbiome typically includes several steps:

Comprehensive Testing

Functional medicine labs can evaluate stool composition, digestive function, inflammation, and even microbial DNA. These tests give an in-depth picture of how your gut is working and where it’s struggling.

Personalized Nutrition Plans

Healing the microbiome begins with food. Dr. Branham helps patients build meal plans rich in fiber, prebiotics, and anti-inflammatory foods while removing agents that feed the bad bacteria or irritate the gut lining. For some, this might mean eliminating gluten, dairy, or processed sugars; for others, it might mean adding fermented foods or polyphenol-rich plants.

Targeted Supplementation

Not every probiotic is right for every person. Dr. Branham selects supplements based on your specific gut makeup and symptoms. These may include the following:

  • Probiotics: To repopulate and balance your gut flora
  • Prebiotics: To feed healthy microbes
  • Digestive enzymes: To help your body break down food more efficiently
  • L-glutamine and zinc carnosine: To support gut barrier repair
  • Herbal antimicrobials: To reduce overgrowth of harmful bacteria or yeast

Lifestyle Medicine

Because your microbiome responds to your overall environment, Dr. Branham also integrates strategies for stress reduction, better sleep, and regular movement. Techniques such as mindfulness, breathwork, or light exercise can lower stress hormones and improve gut-brain communication.

Gradual Restoration of Balance

Healing the gut microbiome isn’t about taking one supplement and expecting instant results. It’s a process of rebalancing your inner ecosystem. Over time, beneficial bacteria regain dominance, inflammation decreases, digestion improves, and your whole body begins to feel lighter, calmer, and more energetic.

Here’s How You’ll Feel When You Finally Fix Your Gut Microbiome

A healthy microbiome impacts nearly every system in your body. After fixing their gut microbiome, patients often notice improvements in the following areas:

  • Digestive issues: Reduced bloating, constipation, diarrhea, heartburn, and nausea
  • Mood and focus: Less anxiety, brain fog, and irritability
  • Skin health: Reduced acne, eczema, and inflammation
  • Energy: Fewer afternoon crashes and better stamina
  • Immunity: Fewer infections and faster recovery times
  • Hormone balance: Better metabolism, menstrual health, and sleep patterns

Because your gut influences so many processes, fixing the gut microbiome often has a ripple effect across your entire body.

Why Functional Medicine Is Different from Conventional Care

Traditional medicine often treats digestive symptoms with acid blockers, antacids, or anti-inflammatory medications. While these can offer temporary relief and have their place in modern medicine, they rarely address the root cause. Functional medicine focuses on identifying why the microbiome became imbalanced and developing a personalized strategy to restore it naturally.

Dr. Branham’s patients in St. Louis appreciate this holistic, science-based approach because it considers the whole person. It looks at their diet, stress levels, environment, and lifestyle rather than just their lab results or diagnosis.

By working together, you and Dr. Branham can uncover what your body truly needs to heal from the inside out.

Start Your Gut Healing Journey in St. Louis

Have you been wondering how to fix your gut microbiome? If you’ve been living with digestive issues, fatigue, or unexplained inflammation, it might be time to take a closer look at the root causes. With the right testing, nutritional support, and personalized care, you can restore balance to your gut and feel like yourself again.

Dr. Branham is an expert in functional medicine and digestive health, helping patients throughout St. Louis find lasting relief by healing their gut naturally.You don’t have to keep guessing what’s wrong. Take the first step toward restoring your microbiome and reclaiming your health. Schedule a consultation with Dr. Branham today. He’s looking forward to meeting you and helping you feel your best.